What causes migraines? Other than people making wild claims on the Internet without any e… — @distilledscience

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La vidéo TikTok de @distilledscience « What causes migraines? Other than people making wild claims on the Internet without any evidence to back them up….🤯 Ever had a migraine? Then you know it’s WAY more than just a headache. It’s this pounding, debilitating pain that can make you want to crawl into a dark hole and never come out. And scientists have been trying to figure out why they hurt SO much for, like, forever! Well, researchers at University of North Carolina may have cracked *part* of the code! The culprit is this little protein called CGRP. It spikes during a migraine attack, and we knew it was involved in pain, just not how. Turns out, it actually messes with the brain's lymphatic system! Think of your brain like a house with a *lot* of bathrooms, and the lymphatic system is like the internet – a series of tubes, that drain away waste in cerebrospinal fluid. Well, CGRP acts like a wrench, tightening those pipes so fluid can’t flow properly. When the researchers injected CGRP and a traceable dye into the lymphatic vessels, they SAW the drainage *slowing way down*. For added proof, they studied mice that were resistant to CGRP. These mice had *fewer* migraines and didn’t mind bright lights as much. This study is HUGE news for migraine sufferers! Yes it’s a rodent study that needs human replication, but that’s normal for showing detailed mechanisms. This means we might be able to develop new treatments that target this CGRP plumbing problem, instead of ones that just mask the pain. And- One more thing! Migraines are 3-5 times more common in women. Well, the researchers *hypothesize* that hormonal changes throughout a woman’s life, like puberty, pregnancy, and menopause, *might* actually affect how this brain drainage system works. One more thing! Alzheimer’s is [twice as common](https://pubmed.ncbi.nlm.nih.gov/37304073/) in people with migraine, and some mouse models have shown that disrupting the cerebrospinal fluid drainage increases plaque formation. So, stay tuned, because this research could lead to better treatments for everyone! DOI: 10.1172/JCI175616. DOI: 10.1038/s41586-018-0368-8 Image Ref: PMID: 36528776. #Science -#health #migraines #headacherelief » compte 521 317 vues, 32 447 j’aime, 851 commentaires et 9 311 partages dans les indicateurs publics relevés par cet index. Cela représente un taux d’engagement de 8,17 % (j’aime, commentaires et partages rapportés aux vues). Elle a été publiée il y a 28 mois et dure 1 minute 43 secondes. Elle a été enregistrée 6 761 fois.

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Combien de vues cette vidéo TikTok a-t-elle ?

La capture indexée ici affiche 521 317 vues, 32 447 j’aime et 851 commentaires.

Qui a publié cette vidéo TikTok ?

Elle a été publiée par @distilledscience, dont le profil est accessible depuis cette page.

Quel est le taux d’engagement de cette vidéo TikTok ?

D’après les indicateurs relevés, le taux d’engagement est de 8,17 % (j’aime + commentaires + partages rapportés aux vues).

Quand cette vidéo TikTok a-t-elle été publiée ?

Elle a été publiée le 2024-07-24, il y a 28 mois.

Quels hashtags sont utilisés dans cette vidéo ?

La capture relève 2 hashtags, à commencer par #health.

Quelle est la durée de cette vidéo TikTok ?

L’extrait capturé dure 1 minute 43 secondes.